NEW YORK, Apr 10 2026 (IPS) - The past several weeks have marked a significant escalation in hostilities across the Middle East, with tensions rising among Israel, Lebanon, Iran, and the United States following large-scale exchanges of bombardment. Recent statements from U.S. President Donald Trump, including threats of extensive destruction in Iran, have further inflamed regional tensions and complicated ongoing diplomatic efforts. Humanitarian experts warn that these developments risk further destabilizing cross-border relations and could trigger a broader regional conflict.
“Every day this war continues, human suffering grows. The scale of devastation grows. Indiscriminate attacks grow,” said UN Secretary-General António Guterres. “The spiral of death and destruction must stop. To the United States and Israel, it is high time to stop the war that is inflicting immense human suffering and already triggering devastating economic consequences. Conflicts do not end on their own. They end when leaders choose dialogue over destruction. That choice still exists. And it must be made – now.”
In late February, Israel coordinated a series of airstrikes targeting Iranian military infrastructure, triggering retaliatory drone and missile strikes from Iran. According to figures from the UN Office for the Coordination of Humanitarian Affairs (OCHA), over 3.8 million Iranians have been impacted by the war in Iran as of early April. Iran’s Ministry of Health and Medical Education (MoHME) reports that over 2,100 civilians have been killed as of April 3, including 216 children, 251 women and 24 health workers. Over 1,880 children, 4,610 women, and 116 health workers have been injured in that same period.
The scale of destruction to civilian infrastructure across Iran has been particularly severe. The Iranian Red Crescent Society (IRCS) estimates that roughly 115,193 civilian structures have sustained significant damage, including at least 763 schools. Israeli airstrikes have targeted numerous densely populated areas and critical civilian infrastructures, including airports, residential areas, hospitals, schools, industrial facilities, cultural heritage sites, water infrastructure, and a power plant in Khorramshahr, as well as nuclear facilities in Khonab, Yazd, and Bushehr.
Iran’s healthcare system has borne a massive toll, with damage to over 442 health facilities across the nation, disrupting access to lifesaving care for over 10 million people, including 2.2 million children. The Pasteur Institute of Iran—one of the oldest research and public health centers in the Middle East, and a critical source of vaccines for infectious diseases—has been severely damaged, leaving thousands of children increasingly vulnerable. Tofigh Darou, a key producer of pharmaceutical products for chronic conditions such as cancer, has been destroyed, raising broader concerns of a severe, nationwide health crisis.
These challenges are especially pronounced for Iran’s growing population of internally displaced persons (IDPs), which has swelled to approximately 3.2 million since the escalation of hostilities. Iran also currently hosts over 1.65 million refugees. These vulnerable communities are in dire need of access to basic services, many of which have been severely disrupted. IDPs and refugee communities face significant protection risks, alongside critical shortages of healthcare, food, clean water, and financial support for basic needs and relocation assistance.
“Unprovoked attacks by the US and Israel — launched amid diplomatic negotiations and without authorisation from the Security Council — violate the fundamental prohibition on the use of force, sovereign equality, territorial integrity, and the duty to peacefully settle disputes under Article 2 of the UN Charter. They also violate the right to life,” said a coalition of UN experts on April 4. “The targeting of civilians, educational facilities, and medical institutions constitutes a grave violation of international humanitarian law and human rights law….Calls by the US and Israel for Iranians to seize control of their own government are reckless and put countless civilian lives at risk.”
On April 8, the U.S. brokered a two-week ceasefire with Iran, mediated by Pakistan, in an effort to reopen the Strait of Hormuz, a critical waterway and one of the world’s most prominent oil and gas passes, and to de-escalate tensions in the 2026 Iran War. Immediately following the implementation of the ceasefire, Israel launched a series of large-scale airstrikes in Lebanon targeting Hezbollah sites, resulting in widespread damage to civilian infrastructure and a significant loss of human life.
Attacks across Lebanon have been widespread, with Israeli authorities reporting that they had carried out approximately 100 strikes across the country within 10 minutes. Southern Lebanon has experienced immense destruction, along with the southern suburbs of Beirut and the eastern Bekaa Valley, all reporting significant damage to civilian infrastructures. Attacks have been reported in the vicinity of the Hiram Hospital in Al-Aabbassiye near Tyre, as well as on an ambulance on the Islamic Health Authority in Qlaileh, causing three civilian deaths.
Figures from the Office of the United Nations High Commissioner for Human Rights (OHCHR) show that more than 1,500 people had been killed by Israeli airstrikes in Lebanon between early March and April 8, including over 200 women and children. Additional figures from the UN reveal that the attacks on April 8 alone resulted in more than 200 deaths and over 1,000 injuries across Lebanon. Many victims are believed to be still trapped beneath the rubble of destroyed infrastructure, as hospitals and rescue teams struggle to respond amid the overwhelming scale of casualties and urgent humanitarian needs.
“The scale of the killing and destruction in Lebanon today is nothing short of horrific,” said UN Human Rights Chief Volker Türk. “Such carnage, within hours of agreeing to a ceasefire with Iran, defies belief. It places enormous pressure on a fragile peace, which is so desperately needed by civilians. The scale of such actions, coupled with statements by Israeli officials indicating an intention to occupy or even annex parts of southern Lebanon, is deeply troubling. Efforts to bring peace to the wider region will remain incomplete as long as the Lebanese people are living under continuing fire, forcibly displaced, and in fear of further attacks.”
On April 7, U.S. President Donald Trump issued a series of posts on social media in which he warned of potential large-scale destruction in Iran, which elicited significant concern and outrage from regional and international actors. His subsequent partial withdrawal of these comments did little to ease concerns and only further underscored the volatility of the U.S.’s role in foreign affairs.
“Today, the President of the United States again resorted to language that is not only deeply irresponsible but profoundly alarming, declaring that ‘the whole civilization will die tonight, never to be brought back’,” Amir Saeid Iravani, Iran’s ambassador to the UN, told the Security Council on April 7. He added that Trump’ s comments only acted as an open declaration of “intent to commit war crimes and crimes against humanity”, underscoring the troubling precents that the U.S. is setting for international conflicts.
“The announcement of a two-week ceasefire is a welcome step but it is partial, fragile, and incomplete. Most urgently, it does not include Lebanon, where I visited IRC programs last week and where airstrikes, evacuation orders and active hostilities not only continue to threaten civilians but intensify. A ceasefire that leaves one front of the conflict burning risks prolonging the crisis, not resolving it,” said David Miliband, President and CEO of the International Rescue Committee.
“The war in Iran has already triggered a dangerous domino effect, spreading humanitarian need, economic shock, and instability across the region and beyond. This moment must be used to expand the ceasefire, ensure the Strait of Hormuz, Bab el-Mandeb and other critical routes remain open to allow scaled-up humanitarian aid and essential supplies to reach those in need, and to stabilize economies under strain. Without that, the gap between rising needs and shrinking resources will only deepen. Civilians must be given the space to begin rebuilding their lives with dignity which can only happen if there is a permanent cessation in hostilities,” he continued.
IPS UN Bureau Report
